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Christine (1983)

Reference ranges for blood tests

Interpretation



The range is usually defined as the set of values 95 percent of the normal population falls within (that is, 95% prediction interval), or two standard deviations from the mean, although the definition may differ (see Definition of reference range). It is determined by collecting data from vast numbers of laboratory tests.



Plasma or whole blood



All values (except the exceptions below) denote blood plasma concentration, which is approximately 60-100% larger than the actual blood concentration if the amount inside red blood cells (RBCs) is negligible. The precise factor depends on hematocrit as well as amount inside RBCs. Exceptions are mainly those values that denote total blood concentration, and in this article they are:



All values in Hematology – red blood cells (except hemoglobin in plasma)



All values in Hematology – white blood cells



Platelet count (Plt)



A few values are for inside red blood cells only:



Vitamin B9 (Folic acid/Folate) in red blood cells



Mean corpuscular hemoglobin concentration (MCHC)



Units



Mass concentration (g/dL or g/L) is the most common measurement unit in the United States. Is usually given with dL (decilitres) as the denominator in the United States, and usually with L (litres) in, for example, Sweden.



Molar concentration (mol/L) is used to a higher degree in most of the rest of the world, including the United Kingdom and other parts of Europe and Australia and New Zealand.



International units (IU) are based on measured biological activity or effect, or for some substances, a specified equivalent mass.



Enzyme activity (kat) is commonly used for e.g. liver function tests like AST, ALT, LD and -GT in Sweden.



Arterial or venous



If not else specified, a reference range for a blood test is generally the venous range, as the standard process of obtaining a sample is by venipuncture. An exception is for acid-base and blood gases, which are generally given for arterial blood.



Still, the blood values are approximately equal between the arterial and venous sides for most substances, with the exception of acid-base, blood gases and drugs (used in therapeutic drug monitoring (TDM) assays). Arterial levels for drugs are generally higher than venous levels because of extraction while passing through tissues.



Inaccuracy



Main article: Reference range#Inaccuracy



References range will vary with age, sex, race, diet, use of prescribed or herbal drugs, stress and even the instruments used. The samples may deviate from normal distribution. Furthermore, reference ranges only denote what are usual values in the population, and do not directly correlate with the ranges for optimal health. In case of substantial difference, there may additionally be an optimal range specified for the substance. Finally, the test procedure itself may be erroneous or inaccurate.



Sorted by concentration



A separate printable combined image is available for mass and molarity



Smaller, narrower boxes indicate a more tight homeostatic regulation when measured as standard “usual” reference range.



By mass and molarity



Hormones predominate at the left part of the scale, shown with a red at ng/L or pmol/L, being in very low concentration. There appears to be the greatest cluster of substances in the yellow part (g/L or nmol/L), becoming sparser in the green part (mg/L or mol/L). However, there is another cluster containing many metabolic substances like cholesterol and glucose at the limit with the blue part (g/L or mmol/L).



To translate a substance from the molar to the mass concentration scale above:



Numerically: molar concentration x molar mass = mass concentration



Measured directly in distance on the scales:



, where distance is in number of decades or “octaves” to the right the mass concentration is found. To translate from mass to molar concentration, the dividend (molar mass and the divisor (1000) in the division change places, or, alternatively, distance to right is changed to distance to left. Substances with a molar mass around 1000g/mol (e.g. thyroxine) are almost vertically aligned in the mass and molar images. Adrenocorticotropic hormone, on the other hand, with a molar mass of 4540, is 0.7 decades to the right in the mass image. Substances with molar mass below 1000g/mol (e.g. electrolytes and metabolites) would have “negative” distance, that is, masses deviating to the left.



Many substances given in mass concentration are not given in molar amount because they haven’t been added to the article.



By units



Units don’t necessarily tell anything about molarity or mass.



A few substances are below this main interval, e.g. thyroid stimulating hormone, being measured in mU/L, or above, like rheumatoid factor and CA19-9, being measured in U/mL.



By enzyme activity



White blood cells



Clinical biochemistry



Clinical chemistry (also known as “clinical biochemistry”, “chemical pathology” or “pure blood chemistry”) is the area of pathology that is generally concerned with analysis of bodily fluids.



Electrolytes and Metabolites



Electrolytes and Metabolites: For iron and copper, some related proteins are also included.



Test


Patient type



Lower limit


Upper limit



Unit



Comments



Sodium (Na)



135, 137



145, 147



mmol/L or mEq/L



31 , 32



33 , 34



mg/dl



Potassium (K)



3.5 , 3.6



5.0 , 5.1



mmol/L or mEq/L



See hypokalemia or hyperkalemia



14



20



mg/dl



Chloride (Cl)



95, 98, 100



105, 106, 110



mmol/L or mEq/L



340



370



mg/dl



Osmolality



275, 280, 281



295, 296, 297



mOsm/kg



Plasma weight excludes solutes



Osmolarity



Slightly less than osmolality



mOsm/l



Plasma volume includes solutes



Urea



1.2, 3.0



3.0, 7.0



mmol/L



BUN – blood urea nitrogen



7



18, 21



mg/dL



* Uric acid



0.18



0.48



mmol/L



Female



2.0



7.0



mg/dL



Male



2.1


8.5



mg/dL



Creatinine



male



60 , 68



90 , 118



mol/L



May be complemented with creatinine clearance



0.7 , 0.8



1.0 , 1.3



mg/dL



female



50 , 68



90 , 98



mol/L



0.6 , 0.8



1.0 , 1.1



mg/dL



BUN/Creatinine Ratio



5



35



-



Plasma glucose (fasting)



3.8 , 4.0



6.0 , 6.1



mmol/L



See also glycosylated hemoglobin (in hematology)



65, 70, 72



100, 110



mg/dL



Full blood glucose (fasting)



3.3



5.6



mmol/L



60



100



mg/dL



Total serum iron (TSI)



male



65, 76



176, 198



g/dL



11.6 , 13.6



30, 32, 35



mol/L



female



26, 50



170



g/dL



4.6 , 8.9



30.4



mol/L



newborns



100



250



g/dL



18



45



mol/L



children



50



120



g/dL



9



21



mol/L



Total iron-binding capacity (TIBC)



240, 262



450, 474



g/dL



43 , 47



81 , 85



mol/L



Transferrin



190, 194, 204



326, 330, 360



mg/dL



25



45



mol/L



Transferrin saturation



20



50



 %



Ferritin



Male



12



300



ng/mL



27


670



pmol/L



Female



12



150



ng/mL



27


330



pmol/L



Ammonia



10, 20



35, 65



mol/L



17 , 34



60 , 110



g/dL



Copper



70



150



g/dL



11


24



mol/L



Ceruloplasmin



15



60



mg/dL



1


4



mol/L



Lactate (Venous)



4.5



19.8



mg/dL



0.5



2.2



mmol/L



Lactate (Arterial)



4.5



14.4



mg/dL



0.5



1.6



mmol/L



Pyruvate



300



900



g/dL



34


102



mol/L



Acid-base and blood gases



Further information: Acid-base homeostasis



Further information: Arterial blood gas



If arterial/venous is not specified for a acid-base or blood gas value, then it generally refers to arterial, and not venous which otherwise is standard.



Acid-base and blood gases are among the few blood constituents that exhibit substantial difference between arterial and venous values. Still, pH, bicarbonate and base excess show a high level of inter-method reliability between arterial and venous tests, so arterial and venous values are roughly equivalent for these.



Test



Arterial/Venous



Lower limit



Upper limit



Unit



Comments



pH



Arterial



7.34, 7.35



7.44, 7.45



Venous



7.31



7.41



[H+]



Arterial



36



44



nmol/L



3.6


4.4



ng/dL



Base excess



Arterial & venous



-3



+3



mEq/L



oxygen pressure (pO2)



Arterial



10 , 11



13 , 14



kPa



75, 83



100, 105



mmHg or torr



Venous



4.0



5.3



kPa



30



40



mmHg or torr



Oxygen saturation



Arterial



94, 95, 96



100



 %



Venous



Approximately 75



Carbon dioxide (CO2)



Arterial



4.4, 4.7



5.9 , 6.0



kPa



Designated pCO2



33, 35



44, 45



mmHg or torr



23



30



mmol/L



100



132



mg/dL



Venous



5.5



6.8



kPa



41



51



mmHg or torr



Bicarbonate (HCO3, )



Arterial & venous



18



23



mmol/L



110



140



mg/dL



Standard bicarbonate (SBCe)



Arterial & venous



21-22



27-28



mmol/L or mEq/L



134



170



mg/dL



Liver function



Further information: Liver function tests



Test



Patient type



Lower limit



Upper limit



Unit



Comments



Total Protein



60, 63



78, 82, 84



g/L



see hypoproteinemia



Albumin



35



48, 55



g/L



see hypoalbuminemia



3.5



4.8, 5.5



U/L



540



740



mol/L



Globulins



23



35



g/L



Total Bilirubin



1.7, 2, 3.4, 5



17, 22, 25



mol/L



0.1, 0.2, 0.29



1.0, 1.3, 1.4



mg/dL



Direct/Conjugated Bilirubin



0.0 or N/A



5 , 7



mol/L



0



0.3, 0.4



mg/dL



Alanine transaminase (ALT/ALAT)



1, 5, 7, 8



20, 21, 56



U/L



Also called serum glutamic pyruvic transaminase (SGPT)



Female



0.15



0.75



kat/L



Male



0.15



1.1



Aspartate transaminase (AST/ASAT)



Female



6



34



IU/L



Also called



serum glutamic oxaloacetic transaminase (SGOT)



0.25



0.60



kat/L



Male



8



40



IU/L



0.25



0.75



kat/L



Alkaline phosphatase (ALP)



Female



42



98



U/L



Male



53



128



(Enzyme activity)



0.6



1.8



kat/L



Gamma glutamyl transferase (GGT)



5 , 8



40, 78



U/L



Cardiac tests



Test



Lower limit



Upper limit



Unit



Comments



Creatine kinase (CK) – male



24, 38, 60



174 , 320



U/L



or ng/mL



Creatine kinase (CK) – female



24, 38, 96



140 , 200



CK-MB



0



3, 3.8, 5



ng/mL or g/L



Troponin Values 12 hrs after onset of pain:



Test



Lower limit



Upper limit



Unit



Comments



Troponin-T



0.02



ng/mL or g/L



Upper limit of normal



Troponin-I



0.2



ng/mL or g/L



Upper limit of normal



Troponin-T



0.02



0.10



ng/mL or g/L



Acute Coronary Syndrome



Troponin-I



0.2



1.00



ng/mL or g/L



Acute Coronary Syndrome



Troponin-T



0.10



n/a



ng/mL or g/L



Myocardial Infarction likely



Troponin-I



1.00



n/a



ng/mL or g/L



Myocardial Infarction likely



Other enzymes and proteins



Test



Lower limit



Upper limit



Unit



Comments



Lactate dehydrogenase (LDH)



50



150



U/L



0.4



1.7



mol/L



LDH (enzyme activity)



1.8



3.4



kat/L



< 70 years old



Amylase



25, 30, 53



110, 120, 123, 125, 190



U/L



0.15



1.1



kat/L



C-reactive protein (CRP)



n/a



5, 6



mg/L



200 , 240



nmol/L



D-dimer



n/a



500



ng/mL



Higher in pregnant women



0.5



mg/L



Lipase



7, 10, 23



60, 150, 208



U/L



Angiotensin-converting enzyme (ACE)



23



57



U/L



Acid phosphatase



3.0



ng/mL



Eosinophil cationic protein (ECP)



2.3



16



g/L



Other ions and trace metals



Further information: Trace metals



Test



Lower limit



Upper limit



Unit



Ionized calcium (Ca)



1.03 , 1.10



1.23 , 1.30



mmol/L



4.1 , 4.4



4.9 , 5.2



mg/dL



Total calcium (Ca)



2.1 , 2.2



2.5, 2.6, 2.8



mmol/L



8.4, 8.5



10.2, 10.5



mg/dL



Phosphate (HPO42)



0.8



1.5


mmol/L



Inorganic phosphorus (serum)



1.0



1.5



mmol/L



3.0



4.5



mg/dL



Copper (Cu)



11



24



mol/L



Zinc (Zn)



60 , 72



110 , 130



g/dL



9.2 , 11



17 , 20



mol/L



Magnesium



1.5 , 1.7



2.0 , 2.3



mEq/L or mg/dL



0.6 , 0.7



0.82 , 0.95



mmol/L



Selenium (optimal range)



120



g/L



Lipids



Further information: Blood lipids



Test



Patient type



Lower limit



Upper limit



Unit



Therapeutic target



Triglycerides



10 39 years



54



110



mg/dL



< 100 mg/dL



or 1.1 mmol/L



0.61



1.2


mmol/L



40 59 years



70



150



mg/dL



0.77



1.7



mmol/L



> 60 years



80



150



mg/dL



0.9



1.7



mmol/L



Total cholesterol



3.0 , 3.6



5.0, 6.5



mmol/L



< 3.9


120, 140



200, 250



mg/dL



< 150


HDL cholesterol



female



1.0, 1.2, 1.3



2.2



mmol/L



> 1.0 mmol/L


> 40 or 60 mg/dL



40 , 50



86



mg/dL



HDL cholesterol



male



0.9



2.0



mmol/L



35



80



mg/dL



LDL cholesterol



(Not valid when



triglycerides >5.0 mmol/L)



2.0, 2.4



3.0 , 3.4



mmol/L



< 2.5


80 , 94



120 , 130



mg/dL



< 100



LDL/HDL quotient



n/a



5



(unitless)



Tumour markers



Further information: Tumour markers



Test



Lower limit



Upper limit



Unit



Comments



Alpha fetoprotein (AFP)



0



44



ng/mL



Beta Human chorionic gonadotrophin (bHCG)



n/a



5



IU/l or mU/ml



in male and non-pregnant female



CA19-9



n/a



40



U/ml



CA-125



n/a



30 , 35



kU/L or U/mL



Carcinoembryonic antigen (CEA)



non-smokers at 50 years



n/a



3.4 , 3.6


g/l



Carcinoembryonic antigen (CEA)



non-smokers at 70 years



n/a



4.1



g/l



Carcinoembryonic antigen (CEA) – smokers



n/a



5



g/l



Prostate specific antigen (PSA)



n/a



2.5 , 4



g/L or ng/mL



below age 45 <2,5 g/L



PAP



0



3



units/dL (Bodansky units)



Thyroid hormones



Further information: Thyroid hormone



Test



Patient type



Lower limit



Upper limit



Unit



Thyroid stimulating hormone



(TSH or thyrotropin)



Adults -



standard range



0.3, 0.4, 0.5, 0.6



4.0, 4.5, 6.0



mIU/L or IU/mL



Adults -



optimal range



0.3 , 0.5



2.0 , 3.0



mIU/L or IU/mL



Infants



1.3



19



mIU/L or IU/mL



Free thyroxine (FT4)



Normal adult



0.7 ,0.8



1.4, 1.5



ng/dL



9, 10, 12


18 , 23



pmol/L



Infant 0-3 d



2.0



5.0



ng/dL



26



65



pmol/L



Infant 3-30 d



0.9



2.2



ng/dL



12



30



pmol/L



Child/Adolescent



31 d – 18 y



0.8



2.0



ng/dL



10



26



pmol/L



Pregnant



0.5



1.0



ng/dL



6.5



13



pmol/L



Total thyroxine



60



140, 160



nmol/L



4, 5.5



11, 12.3



g/dL



Free triiodothyronine (FT3)



Normal adult



0.2



0.5



ng/dL



3.1



7.7



pmol/L



Children 2-16 y



0.1



0.6



ng/dL



1.5



9.2



pmol/L



Total triiodothyronine



0.9 , 1.1



2.5 , 2.7



nmol/L



60, 75



175, 181



ng/dL



Thyroxine-binding globulin (TBG)



12



30



mg/L



Thyroglobulin (Tg)



1.5



30



pmol/L



1



20


g/L



Sex hormones



Further information: Sex steroid



Test



Patient type



Lower limit



Upper limit



Unit



Testosterone



Male, overall



8 , 10



27 , 35



nmol/L



230 , 300


780 – 1000



ng/dL



Male < 50 years



10



45



nmol/L



290



1300



ng/dL



Male > 50 years



6.2



26



nmol/L



180



740



ng/dL



Female



0.7



2.8 – 3.0



nmol/L



20



80 – 85



ng/dL



17 Hydroxyprogesterone



male



0.06



3.0



mg/L



Female (Follicular phase)



0.2



1.0



mg/L



Follicle-stimulating hormone (FSH)



Prepubertal



<1


3



IU/L



Adult male



1



8


Adult female (follicular



and luteal phase)



1



11



Adult female (Ovulation)



6



95% PI (standard)



26



95% PI)



5



90% PI (used in diagram)



15



(90% PI)



Post-menopausal female



30



118



Luteinizing hormone (LH)



Female, peak



20



90% PI (used in diagram)



75



(90% PI)



IU/L



Female, post-menopausal



15



60


Estradiol (an estrogen)



Adult male



50



200


pmol/L



1.4



5.5



ng/dL



Adult female (follicular phase, day 5)



70



95% PI (standard)



500


95% PI



pmol/L



110



90% PI (used in diagram)



220



90% PI



1.9 (95% PI)



14 (95% PI)



ng/dL



3.0 (90% PI)



6.0 (90% PI)



Adult female (preovulatory peak)



400



1500



pmol/L



11



41



ng/dL



Adult female (luteal phase)



70



600



pmol/L



1.9



16



ng/dL



Post-menopausal female



N/A


< 130



pmol/L



N/A



< 3.5



ng/dL



Progesterone



Female at day of ovulation



2.2 (90% PI)



9 (90% PI)



nmol/L



70 (90% PI)



280 (90% PI)



ng/dL



Androstenedione



Adult male and female



60



270



ng/dL



Post-menopausal female



< 180



Prepubertal



< 60



Other hormones



Further information: Hormones



Test



Patient type



Lower limit



Upper limit



Unit



Adrenocorticotropic hormone (ACTH)



4.4



18 ,22



pmol/L



20



80 , 100



pg/mL



Cortisol



09:00 am



140



700



nmol/L



5



25



g/dL



Midnight



80



350



nmol/L



2.9



13



g/dL



Growth hormone (fasting)



0



5



ng/mL



Growth hormone (arginine stimulation)



7



n/a



ng/mL



Prolactin



Female



n/a



20



ng/mL or g/L



Male



15



Parathyroid hormone (PTH)



10 , 17



65 , 70



pg/mL



1.1 , 1.8



6.9 , 7.5



pmol/L



25-hydroxycholecalciferol (a vitamin D)



-Standard reference range



8 , 9



40 , 80



ng/mL



20 , 23



95 , 150



nmol/L



25-hydroxycholecalciferol



-Therapeutic target range



30 , 40



65 , 100



ng/mL



85 , 100



120 , 160



nmol/L



Amino acids



Test



Sex



Age



Lower limit



Upper limit



Unit



Elevated



Therapeutic target



Homocysteine



Female



1219 years



3.3


7.2



mol/L



> 10.4 mol/L



or



> 140 g/dl



< 6.3 mol/L


or



< 85 g/dL



45



100



g/dL



>60 years



4.9


11.6


mol/L



66



160



g/dL



Male



1219 years



4.3


9.9


mol/L



> 11.4 mol/L



or



> 150 g/dL



60



130



g/dL



>60 years



5.9


15.3


mol/L



80



210



g/dL



Vitamins



Test



Patient type



Standard range



Unit



Optimal range



Lower limit



Upper limit



Lower limit



Upper limit



Vitamin A



30



65



g/dL



Vitamin B9



(Folic acid/Folate) – Serum



Age > 1year



3.0



16



ng/mL or g/L



5


6.8



36



nmol/l



11



Vitamin B9



(Folic acid/Folate) – Red blood cells



200



600



ng/mL or g/L



450



1400



nmol/L



Pregnant



ng/mL or g/L



400



nmol/L



900



Vitamin B12 (Cobalamin)



130 , 160



700 , 950



ng/L



100 , 120



520 , 700



pmol/L



Vitamin C (Ascorbic acid)



0.4



1.5



mg/dL



0.9



23



85



mol/L



50



25-hydroxycholecalciferol (a vitamin D)



8 , 9



40 , 80



ng/mL



30 , 40



65 , 100



20 , 23



95 , 150



nmol/L



85 , 100



120 , 160



Vitamin E



mol/L



28



mg/dL



1.2



Toxins



Test



Limit type



Limit



Unit



Lead



Optimal health range



< 20 or 40



g/dL



Ethanol



Limit for drunk driving



0, 0.2, 0.8



or g/L



17.4



mmol/L



Hematology



Hematology is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases.



Red blood cells



These values (except Hemoglobin in plasma) are for total blood and not only blood plasma.



Test



Patient



Lower limit



Upper limit



Unit



Comments



Haemoglobin (Hb)



male



2.0 , 2.1



2.5 , 2.7



mmol/L



Higher in neonates, lower in children.



130, 132, 135



162, 170, 175



g/L



female



1.8 , 1.9



2.3 , 2.5



mmol/L



Sex difference negligible until adulthood.



120


150, 152, 160



g/L



Hemoglobin in plasma



0.16



0.62



mol/L



Normally diminutive compared with inside red blood cells



1



4



mg/dL



Glycosylated hemoglobin (HbA1c)



< 50 years



3.6



5.0



 % of Hb



> 50 years



3.9



5.3



Haptoglobin



< 50 years



0.35



1.9



g/L



> 50 years



0.47



2.1



Haematocrit (Hct)



male



0.39, 0.4, 0.41, 0.45



0.50, 0.52,0.53 , 0.62



female



0.35, 0.36,0.37



0.46, 0.48



Child



0.31



0.43



Mean cell volume (MCV)



Male



76, 82



100, 102



fL



Cells are larger in neonates, though smaller in other children.



Female



78



101



fL



Red blood cell distribution width (RDW)



11.5



14.5



 %



Mean cell haemoglobin (MCH)



0.39



0.54



fmol/cell



25, 27



32, 33, 35



pg/cell



Mean corpuscular hemoglobin concentration (MCHC)



31, 32



35, 36



g/dL



4.8 , 5.0



5.4 , 5.6



mmol/L



Erythrocytes/Red blood cells (RBC)



male



4.2, 4.3



5.7, 5.9, 6.2, 6.9



x1012/L



Female



3.5, 3.8, 3.9



5.1, 5.5



x1012/L



Infant/Child



3.8



5.5



x1012/L



Reticulocytes



26



130



x109/L



Adult



0.5



1.5



 % of RBC



Newborn



1.1



4.5



 % of RBC



Infant



0.5



3.1



 % of RBC



White blood cells



These values are for total blood and not only blood plasma.



Test



Patient type



Lower limit



Upper limit



Unit



White Blood Cell Count (WBC.)



Adult



3.5, 3.9, 4.1, 4.5



9.0, 10.0, 10.9, 11



x109/L



x103/mm3 or



x103/L



Newborn



9



30



1 year old



6



18



Neutrophil granulocytes



(A.K.A. grans, polys, PMNs, or segs)



Adult



1.3, 1.8, 2



5.4, 7, 8



x109/L



45-54



62, 74



 % of WBC



Newborn



6



26



x109/L



Neutrophilic band forms



Adult



0.7



x109/L



3



5



 % of WBC



Lymphocytes



Adult



0.7 , 1.0



3.5, 3.9, 4.8



x109/L



16-25



33, 45



 % of WBC



Newborn



2



11



x109/L



Monocytes



Adult



0.1, 0.2



0.8



x109/L



3, 4.0



7, 10



 % of WBC



Newborn



0.4



3.1



x109/L



Mononuclear leukocytes



(Lymphocytes + monocytes)



Adult



1.5



5



x109/L



20



35



 % of WBC



CD4+ cells



Adult



0.4 , 0.5



1.5 , 1.8



x109/L



Eosinophil granulocytes



Adult



0.0, 0.04



0.44, 0.45, 0.5



x109/L



1



3, 7



 % of WBC



Newborn



0.02



0.85



x109/L



Basophil granulocytes



Adult



40



100, 200, 900



x106/L



0.0



0.75, 2



 % of WBC



Newborn



0.64


x109/L



Coagulation



Test



Lower limit



Upper limit



Unit



Comments



Platelet/Erythrocyte count (Plt)



140, 150



350, 400, 450



x109/L



Prothrombin time (PT)



10, 11, 12



13, 13.5, 14, 15



s



PT reference varies between laboratory kits – INR is standardised



INR



0.9



1.2



The INR is a corrected ratio of a patients PT to normal



Activated partial thromboplastin time (APTT)



18 , 30



28, 42, 45



s



Thrombin clotting time (TCT)



11



18



s



Fibrinogen



1.7, 2.0



3.6 , 4.2



g/L



Antithrombin



0.80



1.2



kIU/L



Bleeding time



2



9



minutes



Viscosity



1.5



1.72



cP



Immunology



Category



Test



Patient



Lower limit



Upper limit



Unit



Comments



Acute phase protein



markers of Inflammation



Erythrocyte sedimentation rate



(ESR)



Male



0



Age2



mm/hr



ESR increases with age and tends to be higher in females.



Female



(Age+10)2


C-reactive protein (CRP)



n/a



5, 6



mg/L



200 , 240



nmol/L



Alpha 1-antitrypsin (AAT)



20 , 22



38 , 53



mol/L



89 , 97



170 , 230



mg/dL



Immunoglobulins



IgA



Adult



70 , 110



360 , 560



mg/dL



IgD



0.5



3.0



IgE



0.01



0.04



IgG



800



1800



IgM



54



220



Autoantibodies



Antinuclear antibodies (ANA)



Extractable nuclear antigen (ENA)



Rheumatoid factor (RF)



0



20-30



IU/mL



High levels not specific for Rheumatoid Arthritis alone.



Serology



Antistreptolysin O titre



(ASOT)



Preschoolers



n/a



100



units/mL



School age



250



Adult



125



See also



Blood test



Cardiology diagnostic tests and procedures



Comprehensive metabolic panel



Medical technologist



Reference range



References



^ Page 34: Units of measurement in Medical toxicology By Richard C. Dart Edition: 3, illustrated Published by Lippincott Williams & Wilkins, 2004 ISBN 0781728452, 9780781728454 1914 pages



^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by bz ca cb cc cd ce cf cg ch ci cj ck cl cm cn co cp cq cr cs ct cu cv cw cx cy cz da db dc dd de df dg dh di dj dk dl dm dn do dp dq dr ds dt du dv dw dx dy Reference range list from Uppsala University Hospital (“Laborationslista”). Artnr 40284 Sj74a. Issued on April 22, 2008



^ a b c Arterial versus venous reference ranges – Brief Article Medical Laboratory Observer, April, 2000 by D. Robert Dufour



^ PROOPIOMELANOCORTIN; NCBI –> POMC Retrieved on September 28, 2009



^ a b c Unless else specified in boxes, then ref is: Ashwood, Edward R.; Tietz, Norbert W.; Burtis, Carl A. (1994). Tietz textbook of clinical chemistry (2nd ed.). Philadelphia: Saunders. ISBN 0-7216-4472-4. 



^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by bz ca cb cc cd ce cf cg ch ci cj ck cl cm cn co cp cq cr cs ct cu cv cw cx cy cz da db dc dd Last page of Deepak A. Rao; Le, Tao; Bhushan, Vikas (2007). First Aid for the USMLE Step 1 2008 (First Aid for the Usmle Step 1). McGraw-Hill Medical. ISBN 0-07-149868-0. 



^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by bz ca cb cc cd ce cf cg ch ci cj ck cl cm cn co cp cq cr cs ct cu cv cw cx cy cz da db dc Normal Reference Range Table from The University of Texas Southwestern Medical Center at Dallas. Used in Interactive Case Study Companion to Pathologic basis of disease.



^ a b c d Derived from molar values using molar mass of 22.99mol1



^ a b Derived from molar values using molar mass of 39.10mol1



^ a b c d e f g h i j k l m n MERCK MANUALS > Common Medical Tests > Blood Tests Last full review/revision February 2003



^ a b Derived from molar values using molar mass of 35.45mol1



^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by Blood Test Results – Normal Ranges Bloodbook.Com



^ a b Gardner MD, Scott R (April 1980). “Age- and sex-related reference ranges for eight plasma constituents derived from randomly selected adults in a Scottish new town”. J. Clin. Pathol. 33 (4): 3805. doi:10.1136/jcp.33.4.380. PMID 7400337. PMC 1146084. http://jcp.bmj.com/cgi/pmidlookup?view=long&pmid=7400337. 



^ a b c d Finney H, Newman DJ, Price CP (January 2000). “Adult reference ranges for serum cystatin C, creatinine and predicted creatinine clearance”. Ann. Clin. Biochem. 37 ( Pt 1): 4959. doi:10.1258/0004563001901524. PMID 10672373. http://acb.rsmjournals.com/cgi/pmidlookup?view=long&pmid=10672373. 



^ a b c d e f g h Derived from molar values by multiplying with the molar mass of 113.118 g/mol, and divided by 10.000 to adapt from g/L to mg/dL



^ a b MedlinePlus Encyclopedia Glucose tolerance test



^ a b c Derived from molar values using molar mass of 180g/mol



^ a b c d e f g h i j k Slon S (2006-09-22). “Serum Iron”. University of Illinois Medical Center. http://uimc.discoveryhospital.com/main.php?t=enc&id=1456. Retrieved 2006-07-06. 



^ a b c d Diagnostic Chemicals Limited > Serum Iron-SL Assay July 15, 2005



^ a b c d e f g h i j k l m Derived from mass values using molar mass of 55.85mol1



^ a b Table 1. Page 133. Clinical Chemistry 45, No. 1, 1999 (stating 1.93.3 g/L)



^ a b Derived by dividing mass values with molar mass



^ a b c d Ferritin by: Mark Levin, MD, Hematologist and Oncologist, Newark, NJ. Review provided by VeriMed Healthcare Network



^ a b c d Derived from mass values using molar mass of 450,000mol1



^ a b Mitchell ML, Filippone MD, Wozniak TF (August 2001). “Metastatic carcinomatous cirrhosis and hepatic hemosiderosis in a patient heterozygous for the H63D genotype”. Arch. Pathol. Lab. Med. 125 (8): 10847. PMID 11473464. http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=125&page=1084. 



^ a b Diaz J, Tornel PL, Martinez P (July 1995). “Reference intervals for blood ammonia in healthy subjects, determined by microdiffusion”. Clin. Chem. 41 (7): 1048. PMID 7600690. 



^ a b c d Derived from molar values using molar mass of 17.03 g/mol



^ a b Derived from mass values using molar mass of 63.55mol1



^ a b Derived from mass using molar mass of 151kDa



^ a b c d Derived from mass values using molar mass of 90.08 g/mol



^ a b Derived from mass values using molar mass of 88.06 g/mol



^ Middleton P, Kelly AM, Brown J, Robertson M (August 2006). “Agreement between arterial and central venous values for pH, bicarbonate, base excess, and lactate”. Emerg Med J 23 (8): 6224. doi:10.1136/emj.2006.035915. PMID 16858095. 



^ a b c d e f g h i j k l The Medical Education Division of the Brookside Associates–> ABG (Arterial Blood Gas) Retrieved on Dec 6, 2009



^ a b Derived from molar values using molar mass of 1.01mol1



^ a b c d e f g h Derived from mmHg values using 0.133322 kPa/mmHg



^ a b Derived from molar values using molar mass of 44.010 g/mol



^ a b c d Derived from molar values using molar mass of 61 g/mol



^ Reference range (albumin) at GPnotebook



^ a b Derived from mass using molecular weight of 65kD



^ a b c d e Derived from mass values using molar mass of 585g/mol



^ a b Derived from molar values using molar mass of 585g/mol



^ a b c d e f g h i j k l m n o p q r s Fachwrterbuch Kompakt Medizin E-D/D-E. Author: Fritz-Jrgen Nhring. Edition 2. Publisher:Elsevier, Urban&FischerVerlag, 2004. ISBN 3437151207, 9783437151200. Length: 1288 pages



^ a b c d GPnotebook > reference range (AST) Retrieved on Dec 7, 2009



^ a b Creatine kinase at GPnotebook



^ a b c d e f g h i j South London Healthcare NHS Trust



^ Reference range (amylase) at GPnotebook



^ a b C-reactive protein at GPnotebook



^ a b 2730 Serum C-Reactive Protein values in Diabetics with Periodontal Disease A.R. Choudhury, and S. Rahman, Birdem, Diabetic Association of Bangladesh, Dhaka, Bangladesh. (the diabetics were not used to determine the reference ranges)



^ a b c d Derived from mass using molar mass of 25,106 g/mol



^ Plasma Measurement of D-Dimer Levels for the Early Diagnosis of Ischemic Stroke Subtypes Walter Ageno, MD; Sergio Finazzi, MD; Luigi Steidl, MD; Maria Grazia Biotti, MD; Valentina Mera, MD; GianVico Melzi d’Eril, MD; Achille Venco, MD. Arch Intern Med. 2002;162:2589-2593.



^ Kline JA, Williams GW, Hernandez-Nino J (May 2005). “D-dimer concentrations in normal pregnancy: new diagnostic thresholds are needed”. Clinical chemistry 51 (5): 8259. doi:10.1373/clinchem.2004.044883. PMID 15764641. http://www.clinchem.org/cgi/content/full/51/5/825. 



^ a b Larsson L, Ohman S (November 1978). “Serum ionized calcium and corrected total calcium in borderline hyperparathyroidism”. Clin. Chem. 24 (11): 19625. PMID 709830. http://www.clinchem.org/cgi/pmidlookup?view=long&pmid=709830. 



^ a b c d Derived from molar values using molar mass of 40.08 mol1



^ a b c Derived from mass values using molar mass of 40.08 mol1



^ Walter F., PhD. Boron (2005). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3.  Page 849



^ Reference range for copper at GPnotebook



^ a b http://www.dlolab.com/PDFs/DLO-OCTOBER-2008-LAB-UPDATE.pdf



^ a b Derived from molar values using molar mass of 65.38 g/mol



^ a b Derived from mass values using molar mass of 65.38 g/mol



^ a b Derived from molar values using molar mass of 24.31/mol



^ a b Derived from mass values using molar mass of 24.31/mol



^ a b c d e f g h i j k l m n o Adeva Nutritionals Canada > Optimal blood test values Retrieved on July 9, 2009



^ a b c d e f Derived from values in mg/dl to mmol/l, by dividing by 89, according to faqs.org: What are mg/dl and mmol/l? How to convert? Glucose? Cholesterol? Last Update July 21, 2009. Retrieved on July 21, 2009



^ a b c Derived from values in mg/dl to mmol/l, by dividing by 39, according to faqs.org: What are mg/dl and mmol/l? How to convert? Glucose? Cholesterol? Last Update July 21, 2009. Retrieved on July 21, 2009



^ a b c Reference range (cholesterol) at GPnotebook



^ a b c d e f g h Royal College of Pathologists of Australasia; Cholesterol (HDL and LDL) – plasma or serum Last Updated: Monday, 6 August 2007



^ What Your Cholesterol Levels Mean. American Heart Association. Retrieved on September 12, 2009



^ a b c d e f g h i Derived from values in mmol/l (to mg/dl), by multiplying by 39, according to faqs.org: What are mg/dl and mmol/l? How to convert? Glucose? Cholesterol? Last Update July 21, 2009. Retrieved on July 21, 2009



^ American Association for Clinical Chemistry; HDL Cholesterol



^ GP Notebook > range (reference, ca-125) Retrieved on Jan 5, 2009



^ ClinLab Navigator > Test Interpretations > CA-125 Retrieved on Jan 5, 2009



^ a b Bjerner J, Hgetveit A, Wold Akselberg K, et al. (June 2008). “Reference intervals for carcinoembryonic antigen (CEA), CA125, MUC1, Alfa-foeto-protein (AFP), neuron-specific enolase (NSE) and CA19.9 from the NORIP study”. Scandinavian journal of clinical and laboratory investigation 68: 112. doi:10.1080/00365510802126836. PMID 18609108. 



^ Carcinoembryonic Antigen(CEA) at MedicineNet



^ The TSH Reference Range Wars: What’s “Normal?”, Who is Wrong, Who is Right… By Mary Shomon, About.com. Updated: June 19, 2006. About.com Health’s Disease and Condition



^ a b 2006 Press releases: Thyroid Imbalance? Target Your Numbers Contacts: Bryan Campbell American] Association of Clinical Endocrinologists



^ a b The TSH Reference Range Wars: What’s “Normal?”, Who is Wrong, Who is Right… By Mary Shomon, About.com. Updated: June 19, 2006



^ a b Demers, Laurence M.; Carole A. Spencer (2002). “LMPG: Laboratory Support for the Diagnosis and Monitoring of Thyroid Disease”. National Academy of Clinical Biochemistry (USA). http://www.nacb.org/lmpg/thyroid_LMPG_PDF.stm. Retrieved 2007-04-13.  – see Section 2. Pre-analytic factors



^ a b c d e f g h i j Free T4; Thyroxine, Free; T4, Free UNC Health Care System



^ a b c d e f g h i j Derived from mass values using molar mass of 776.87 g/mol



^ a b c d e f g h i j k l m n o Table 4: Typical reference ranges for serum assays – Thyroid Disease Manager



^ a b c d Euthyroid Patient with Elevated Serum Free Thyroxine George van der Watt1,a, David Haarburger1 and Peter Berman



^ a b c d Derived from mass values using molar mass of 650.98 g/mol



^ a b Serum concentration of free T3, free T4 and TSH in healthy children Cioffi Michele; Gazzerro Patrizia; Vietri Maria Teresa; Magnetta Rosa; Durante Adriana; D’Auria Annamaria; Puca Giovanni Alfredo; Molinari Anna Maria ;



^ a b Andrology Australia: Your Health > Low Testosterone > Diagnosis



^ a b c d Derived from mass values using molar mass of 288.42g/mol



^ a b c d e f g Derived from molar values using molar mass of 288.42g/mol



^ a b c d MedlinePlus > Testosterone Update Date: 3/18/2008. Updated by: Elizabeth H. Holt, MD, PhD, Yale University. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director



^ a b c d e f g h i j reference range (FSH) GPnotebook. Retrieved on September 27, 2009



^ a b c d e f g h Values taken from day 1 after LH surge in: Establishment of detailed reference values for luteinizing hormone, follicle stimulating hormone, estradiol, and progesterone during different phases of the menstrual cycle on the Abbott ARCHITECT analyzer. Reto Stricker, Raphael Eberhart, Marie-Christine Chevailler, Frank A. Quinn, Paul Bischof and Rene Stricker. Clin Chem Lab Med 2006;44(7):883887 PMID: 16776638



^ a b c d e f New York Hospital Queens > Services and Facilities > Patient Testing > Pathology > New York Hospital Queens Diagnostic Laboratories > Test Directory > Reference Ranges Retrieved on Nov 8, 2009



^ a b c d e f g h i j GPNotebook – reference range (oestradiol) Retrieved on September 27, 2009



^ a b c d e f g h i j k l Derived from molar values using molar mass of 272.38g/mol



^ a b Derived from molar values using molar mass of 314.46 g/mol



^ a b Derived from mass values using molar mass of 4540g/mol according to PROOPIOMELANOCORTIN; NCBI –> POMC Retrieved on September 28, 2009



^ “Adrenocorticotropic Hormone:Normal”. WebMD. 09-03-2006. http://children.webmd.com/adrenocorticotropic-hormone?page=2. Retrieved 2008-11-09. 



^ Derived from molar values using molar mass of 4540g/mol according to PROOPIOMELANOCORTIN; NCBI –> POMC Retrieved on September 28, 2009



^ a b c d Biochemistry Reference Ranges at Good Hope Hospital Retrieved on Nov 8, 2009



^ a b c d Derived from molar values using molar mass of 362 g/mol



^ a b Derived from molar values using molar mass of 9.4 kDa



^ a b Table 2 in: Aloia JF, Feuerman M, Yeh JK (2006). “Reference range for serum parathyroid hormone”. Endocr Pract 12 (2): 13744. PMID 16690460. 



^ a b Derived from mass values using molar mass of 9.4 kDa



^ a b c d e f Derived from molar values using molar mass 400.6 g/mol



^ a b c d Bender, David A. (2003). “Vitamin D”. Nutritional biochemistry of the vitamins. Cambridge: Cambridge University Press. ISBN 0-521-80388-8. http://books.google.com.br/books?id=pxEJNs0IUo4C.  Retrieved December 10, 2008 through Google Book Search.



^ a b c d Bischoff-Ferrari, H.A., Dietrich, T., Orav, J.E., Hu, F.B., Zhang, Y., Karlson, E., Dawson-Hughes, B. 2004. Higher 25-hydroxyvitamin D levels are associated with better lower extremity function in both active and inactive adults 60+ years of age. American Journal of Clinical Nutrition. 80:752-758.



^ a b c d Reusch J, Ackermann H, Badenhoop K (May 2009). “Cyclic changes of vitamin D and PTH are primarily regulated by solar radiation: 5-year analysis of a German (50 degrees N) population”. Horm. Metab. Res. 41 (5): 4027. doi:10.1055/s-0028-1128131. PMID 19241329. 



^ a b c d e f g h Letter: Calcium and vitamin D in preventing fractures. Data are not sufficient to show inefficacy Alex Vasquez, researcher. BMJ 2005;331:108-109 (9 July), doi:10.1136/bmj.331.7508.108-b.



^ a b c d e f g h The Doctor’s Doctor: Homocysteine



^ a b c d e f g h Derived from molar values using molar massof 135 g/mol



^ a b c d e f Central Manchester University Hospitals –> Reference ranges Retrieved on July 9, 2009



^ University of Kentucky Chandler Medical Center > Clinical Lab Reference Range Guide Retrieved on April 28, 2009



^ a b c d e Derived from mass values using molar mass of 441 mol1



^ a b c d e f g GPnotebook > B12 Retrieved on April 28, 2009



^ a b Derived form molar values using molar mass of 1355g/mol



^ a b Derived from mass values using molar mass of 1355g/mol



^ a b Derived from mass values using molar mass of 176 grams per mol



^ a b c For Driving under the influence by country, see Drunk driving law by country



^ Derived from mass values using molar mass of 46g/mol



^ a b c d e Derived from mass values using 64,500 g/mol, according to Van Beekvelt MC, Colier WN, Wevers RA, Van Engelen BG (2001). “Performance of near-infrared spectroscopy in measuring local O2 consumption and blood flow in skeletal muscle”. J Appl Physiol 90 (2): 511519. PMID 11160049. 



^ a b c d Derived from mass concentration, using molar mass of 64,458 g/mol (Van Beekvelt MC, Colier WN, Wevers RA, Van Engelen BG (2001). “Performance of near-infrared spectroscopy in measuring local O2 consumption and blood flow in skeletal muscle”. J Appl Physiol 90 (2): 511519. PMID 11160049. ). 1 g/dL = 0.1551 mmol/L



^ a b c d e f g h lymphomation.org > Tests & Imaging > Labs > Complete Blood Count Retrieved on May 14, 2009



^ a b c d e f g h i j k l m n o p q r s t u Clinical Laboratory Medicine. By Kenneth D. McClatchey. Page 807.



^ Determination of monocyte count by hematological analyzers, manual method and flow cytometry in polish population Central European Journal of Immunology 1-2/2006. (Centr Eur J Immunol 2006; 31 (1-2): 1-5) authors: Elbieta Grska, Urszula Demkow, Roman Pikowski, Barbara Jakubczak, Dorota Matuszewicz, Jolanta Gawda, Wioletta Rzeszotarska, Maria Wsik,



^ a b MedlinePlus Encyclopedia 003652



^ a b Retrieved on November 20, 2009



^ a b Miller A, Green M, Robinson D (1983). “Simple rule for calculating normal erythrocyte sedimentation rate”. Br Med J (Clin Res Ed) 286 (6361): 266. doi:10.1136/bmj.286.6361.266. PMID 6402065. 



^ Bttiger LE, Svedberg CA (1967). “Normal erythrocyte sedimentation rate and age”. Br Med J 2 (5544): 857. doi:10.1136/bmj.2.5544.85. PMID 6020854. 



^ a b Sipahi T, Kara C, Tavil B, Inci A, Oksal A (March 2003). “Alpha-1 antitrypsin deficiency: an overlooked cause of late hemorrhagic disease of the newborn”. J. Pediatr. Hematol. Oncol. 25 (3): 2745. doi:10.1097/00043426-200303000-00019. PMID 12621252. http://www.jpho-online.com/pt/re/jpho/fulltext.00043426-200303000-00019.htm. 



^ a b Derived from mass values using molar mass of 44324.5 g/mol



^ a b Derived from molar values using molar mass of 44324.5 g/mol



^ a b c d e f g h i j The Society for American Clinical Laboratory Science > Chemistry Tests > Immunoglobulins Retrieved on Nov 26, 2009



External links



biochemical reference values at GPnotebook



Values at lymphomation.org



Descriptions at amarillomed.com



v  d  e



Medical test: Serology, reference range: blood tests



Clinical biochemistry



Metabolic panel



BMP: electrolytes (Na+/K+, Cl-/HCO3-)  renal function, BUN-to-creatinine ratio (BUN/Creatinine)  Glucose  Ca



CMP: BMP + protein tests (Human serum albumin, Serum total protein)  liver function tests (ALP, ALT, AST, Bilirubin)



derived values: Plasma osmolality  Serum osmolal gap



Acid-base homeostasis



Arterial blood gas  Base excess  Anion gap  CO2 content



Iron tests



Transferrin saturation = Serum iron / Total iron-binding capacity



Ferritin  Transferrin  Transferrin receptor



Blood sugar



Glucose test  Glucose tolerance test  Noninvasive glucose  C-peptide  Fructosamine  Glycated hemoglobin



Endocrine



ACTH stimulation test  Thyroid function tests



Cardiac marker



Troponin test  CPK-MB test  Glycogen phosphorylase isoenzyme BB



Other



Beutler test  Blood lipids  Tumor marker



Hematology/CBC



Clotting



Platelet count  Mean platelet volume  vWF: Ristocetin induced platelet agglutination



clotting factors: Prothrombin time  Partial thromboplastin time  Thrombin time



other/general coagulation: Bleeding time  animal enzyme (Reptilase time, Ecarin clotting time, Dilute Russell’s viper venom time)  Thromboelastography



fibrinolysis: Euglobulin lysis time  D-dimer



Red blood cell indices



Hematocrit  Hemoglobin  RBC count



ratios: Mean corpuscular hemoglobin  Mean corpuscular hemoglobin concentration  Mean corpuscular volume



Fetal hemoglobin: Apt-Downey test  Kleihauer-Betke test  Red blood cell distribution width



Reticulocyte index  Haptoglobin



Other



Blood film  Blood viscosity  Absolute neutrophil count



Immunology



Infections



viral infection: HIV (HIV test, BDNA test)  Epstein-Barr virus (Monospot test)



bacterial infection: syphilis (VDRL, Rapid plasma reagin, Wassermann test, FTA-ABS)  rickettsia (Weil-Felix test)  helicobacter (HelicoCARE direct)  streptococcus (Antistreptolysin O titre)



protozoan infection: toxoplasmosis (Sabin-Feldman dye test)



Inflammation



C-reactive protein  Erythrocyte sedimentation rate  MELISA  RAST test



see also reference ranges for blood tests



Categories: Blood tests
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